Description

(13S)-12-Hydroxy-14-Deethylidenecrotalanan-11,15-Dione is a complex pyrrolizidine alkaloid derivative, a compound class of significant interest in advanced organic synthesis and medicinal chemistry research. Its intricate molecular architecture makes it a valuable chiral building block and a key intermediate for the development of novel pharmacologically active molecules. This high-purity compound is primarily utilized by research institutions and pharmaceutical R&D departments focused on synthetic methodology and bioactive compound discovery.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of potential drug candidates, particularly those targeting complex biological pathways.
• Medicinal Chemistry Research: Used as a reference standard or a starting material for structure-activity relationship (SAR) studies in academic and industrial labs.
• Natural Product Synthesis: Acts as a key intermediate in the total synthesis or semi-synthesis of complex natural products within the pyrrolizidine alkaloid family.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme interactions or specific biological mechanisms related to its structural class.
• Advanced Organic Synthesis: Utilized for developing novel synthetic routes and methodologies due to its challenging stereochemistry and functional groups.

Basic Information

Product Name	(13S)-12-Hydroxy-14-Deethylidenecrotalanan-11,15-Dione
CAS No.	49679-23-4
Molecular Formula	C18H23NO5
Molecular Weight	333.38 g/mol
Synonyms	12-Hydroxy-14-deethylidenecrotalanan-11,15-dione, (13S)-; 14-Deethylidenecrotalanan-11,15-dione, 12-hydroxy-, (13S)-; Crotanecine derivative; Pyrrolizidine alkaloid intermediate; 11,15-Dioxo-12-hydroxy-14-deethylidenecrotalanan; (13S)-12-Hydroxy-14-deethylidene-crotalanan-11,15-dione
EINECS	Contact for details

Quality Control

Our (13S)-12-Hydroxy-14-Deethylidenecrotalanan-11,15-Dione is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for research reproducibility. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant research-grade standards, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.