Description

.Alpha.-Canadine Methochloride is a quaternary ammonium alkaloid derivative, specifically the methochloride salt of α-canadine. This compound is of significant interest in advanced organic synthesis and pharmaceutical research due to its role as a key intermediate and reference standard. It is primarily utilized by research institutions and chemical manufacturers focused on developing novel bioactive compounds and studying alkaloid chemistry.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis of novel alkaloid-based drug candidates and active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development, validation, and identification of related compounds.
• Biochemical Studies: Employed in pharmacological and biochemical research to investigate the structure-activity relationships (SAR) of tetrahydroprotoberberine derivatives.
• Chemical Synthesis: Acts as a specialized building block for the preparation of more complex, functionalized molecules in medicinal chemistry.
• Academic Research: Utilized in university and institutional labs for studies in natural product chemistry, organic synthesis, and alkaloid isolation.

Basic Information

Product Name	.Alpha.-Canadine Methochloride
CAS No.	47474-49-7
Molecular Formula	C21H24ClNO4
Molecular Weight	389.87 g/mol
Synonyms	α-Canadine Methochloride; Canadine Methochloride; 5,8,13,13a-Tetrahydro-2,3,10,11-tetramethoxy-6H-dibenzo[a,g]quinolizinium Chloride; 2,3,10,11-Tetramethoxy-5,8,13,13a-tetrahydro-6H-dibenzo[a,g]quinolizinium Chloride; Tetrahydroberberine Methochloride; THB Methochloride
EINECS	Contact for details

Quality Control

Our .Alpha.-Canadine Methochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.