Description

(1R,2R)-(-)-2-Amino-1-Phenyl-1,3-Propanediol is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its defined stereochemistry makes it a critical precursor in the synthesis of enantiomerically pure compounds, particularly for active pharmaceutical ingredients (APIs). This product is essential for manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality chiral synthons for research, development, and production.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of various APIs, including antiviral and cardiovascular drugs.
• Asymmetric Synthesis Catalyst: Used as a ligand or auxiliary in catalytic systems for enantioselective transformations.
• Agrochemical Synthesis: Serves as a building block for creating chiral active ingredients in herbicides and pesticides.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial Research: A valuable compound for methodological development in organic chemistry and process optimization.
• Diagnostic Reagent Preparation: Can be utilized in the development of chiral selectors for analytical chromatography.

Basic Information

Product Name	(1R,2R)-(-)-2-Amino-1-Phenyl-1,3-Propanediol
CAS No.	46032-98-8
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(1R,2R)-2-Amino-1-phenylpropane-1,3-diol; (1R,2R)-(-)-2-Amino-1-phenyl-1,3-propanediol; (-)-2-Amino-1-phenyl-1,3-propanediol; (1R,2R)-APD; D-erythro-2-Amino-1-phenyl-1,3-propanediol; (R,R)-2-Amino-1-phenyl-1,3-propanediol; (1R,2R)-1-Phenyl-2-aminopropane-1,3-diol
EINECS	Contact for details

Quality Control

Our (1R,2R)-(-)-2-Amino-1-Phenyl-1,3-Propanediol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.