Description

Uridine 5′-Diphosphoglucuronic Acid Ammonium Salt is a critical nucleotide sugar essential for glucuronidation, a major phase II detoxification pathway in biological systems. This high-purity biochemical is vital for research and development in drug metabolism and enzymology studies. It is primarily utilized by pharmaceutical researchers, diagnostic manufacturers, and academic institutions focused on biochemistry and molecular biology.

Application

• Enzymology Research: Essential substrate for UDP-glucuronosyltransferase (UGT) enzymes in kinetic and inhibition studies.
• Drug Metabolism & Toxicology (DMPK): Used in in vitro assays to study the glucuronidation of new chemical entities and drug candidates.
• Diagnostic Reagent Manufacturing: A key component in enzymatic kits for clinical diagnostics and research assays.
• Biochemical Synthesis: Serves as a glucuronic acid donor in the enzymatic synthesis of glucuronide conjugates.
• Academic Research: Fundamental tool for investigating liver function, detoxification pathways, and endogenous metabolism.
• Quality Control Reference Standard: Used as a certified reference material in pharmaceutical quality control laboratories.

Basic Information

Product Name	Uridine 5′-Diphosphoglucuronic Acid Ammonium Salt
CAS No.	43195-60-4
Molecular Formula	C15H24N3O18P2 (free acid) • xNH3
Molecular Weight	Contact for details
Synonyms	UDP-Glucuronic Acid Ammonium Salt; UDP-GlcA; UDP-α-D-Glucuronic Acid; Uridine Diphosphate Glucuronic Acid; UDPGA; Uridine 5'-(trihydrogen diphosphate) P'→5'-ester with α-D-glucopyranuronic acid, ammonium salt; 5'-UDP-Glucuronate
EINECS	Contact for details

Quality Control

Our Uridine 5′-Diphosphoglucuronic Acid Ammonium Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and high biological activity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and stability parameters. We adhere to relevant industry guidelines for biochemical reagents to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, desiccate at -20°C. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Biological Activity (Enzymatic Assay)	Conforms
pH (in solution)	6.0 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.