Description

13,14-Dihydro-15-Keto Prostaglandin F2α-D4 CAS NO 42932-59-2 is a deuterated analog of a key prostaglandin metabolite, offering enhanced stability for research applications. This high-purity compound is critical for use as an internal standard in mass spectrometry-based analytical methods, ensuring accurate quantification in complex biological matrices. It is primarily utilized by pharmaceutical R&D laboratories, clinical research organizations, and academic institutions focused on lipidomics, inflammation studies, and metabolic pathway analysis.

Application

• Mass Spectrometry Internal Standard: Essential for the precise quantification of prostaglandin F2α and related metabolites in LC-MS/MS and GC-MS assays.
• Biomarker Research: Used in the development and validation of clinical diagnostic methods for oxidative stress and inflammatory conditions.
• Pharmacokinetic/Pharmacodynamic (PK/PD) Studies: Serves as a stable isotope-labeled tracer to study drug metabolism and the dynamics of arachidonic acid pathways.
• Lipidomics and Metabolomics: A key reference standard for profiling eicosanoids and other oxylipins in biological samples (e.g., plasma, urine, tissue homogenates).
• Quality Control in Pharmaceutical Development: Employed in analytical method development and validation to ensure accuracy and compliance with regulatory guidelines (e.g., FDA, EMA).
• Enzyme Activity Assays: Used as a substrate or reference compound in studies of prostaglandin dehydrogenases and reductases.

Basic Information

Product Name	13,14-Dihydro-15-Keto Prostaglandin F2α-D4
CAS No.	42932-59-2
Molecular Formula	C₂₀H₂₈D₄O₅
Molecular Weight	356.48 g/mol
Synonyms	15-Keto-13,14-dihydro-PGF2α-d4; 15-Keto-dihydro-PGF2α-d4; 9α,11α,15-Trihydroxy-13,14-dihydro-2,3,4,5-tetranor-prost-5-en-1,18-dioic Acid-d4; 15-Keto-DH-PGF2α-d4; Deuterated 15-Keto-13,14-dihydro-Prostaglandin F2α; 15-K-13,14-DH-PGF2α-d4; 9α,11α,15-Trihydroxy-13,14-dihydro-2,3,4,5-tetranor-prosta-5-en-1,18-dioic-2,3,4,5-d4 Acid
EINECS	Contact for details

Quality Control

Every batch of 13,14-Dihydro-15-Keto Prostaglandin F2α-D4 is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, with comprehensive testing via NMR, HPLC, and mass spectrometry to confirm identity, potency, and deuterium enrichment. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.