Description

Peg7-Tos CAS NO 42749-28-0 is a specialized polyethylene glycol derivative functionalized with a tosylate (p-toluenesulfonate) group, where the PEG chain consists of seven ethylene oxide units. This bifunctional compound is a valuable chemical intermediate, prized for its ability to act as a leaving group in nucleophilic substitution reactions, facilitating the controlled introduction of PEG chains onto target molecules. It is primarily sought after by researchers and manufacturers in the pharmaceutical, biotechnology, and specialty chemical sectors for applications in drug delivery, bioconjugation, and polymer synthesis.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing PEGylated active pharmaceutical ingredients (APIs) to enhance solubility, stability, and circulation time.
• Bioconjugation Reagent: Used to attach polyethylene glycol chains (PEGylation) to peptides, proteins, and antibodies, modifying their pharmacokinetic properties.
• Polymer Chemistry: Serves as a functional initiator or monomer in the synthesis of tailored block copolymers and functionalized polymeric materials.
• Surface Modification: Employed to create hydrophilic, non-fouling coatings on medical devices, sensors, and nanomaterials.
• Crosslinking Agent: Utilized in the preparation of hydrogels and polymer networks for controlled release and tissue engineering applications.
• Linker Chemistry: Acts as a spacer or linker in prodrug design and diagnostic agent development.

Basic Information

Product Name	Peg7-Tos
CAS No.	42749-28-0
Molecular Formula	C21H36O10S
Molecular Weight	480.57 g/mol
Synonyms	Poly(ethylene glycol) 7 p-toluenesulfonate; PEG7 Tosylate; 2-[2-[2-[2-[2-[2-[2-(4-Methylbenzenesulfonyloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol; Heptaethylene glycol monotosylate; mPEG7-OTs; 7-EG-Tos; Tos-PEG7-OH; Heptaethylene glycol mono(p-toluenesulfonate)
EINECS	Contact for details

Quality Control

Our Peg7-Tos is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets high-purity standards suitable for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage under inert atmosphere, it is recommended to seal under nitrogen.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.