Description

Harderoporphyrinogen CAS NO 42607-18-1 is a key porphyrinogen intermediate in the biosynthesis of heme and chlorophyll. This compound matters for researchers and manufacturers as it is a crucial precursor for studying metabolic disorders like porphyrias and for developing related biochemical assays. It is primarily needed by the pharmaceutical, biotechnology, and academic research sectors for advanced metabolic studies and diagnostic reagent development.

Application

• Biochemical Research: Used as a critical intermediate in studies of the heme biosynthetic pathway and porphyria diseases.
• Diagnostic Reagent Manufacturing: Serves as a reference standard or precursor in the production of kits for diagnosing enzymatic deficiencies in heme synthesis.
• Pharmaceutical Development: Employed in R&D for novel therapies targeting metabolic disorders related to porphyrin metabolism.
• Enzymology Studies: Acts as a substrate for enzymes like coproporphyrinogen oxidase in kinetic and inhibition studies.
• Academic & Clinical Laboratories: Essential for teaching and research in biochemistry, molecular biology, and clinical pathology.
• Metabolite Standard: Used as a high-purity analytical standard in LC-MS or HPLC for quantifying porphyrinogens in biological samples.

Basic Information

Product Name	Harderoporphyrinogen
CAS No.	42607-18-1
Molecular Formula	C₃₄H₄₀N₄O₈
Molecular Weight	632.70 g/mol
Synonyms	Harderoporphyrinogen; 3-[8-(2-Carboxyethyl)-13,17-bis(2-carboxyethyl)-3,7,12,18-tetramethyl-21,22,23,24-tetraporphyrin-2-yl]propanoic acid; 2,7,13,17-Tetracarboxy-3,8,12,18-tetramethylporphyrinogen; Harderoporphyrin; Porphyrinogen III, 2,7,13,17-tetrakis(2-carboxyethyl)-3,8,12,18-tetramethyl-; A key intermediate between coproporphyrinogen III and protoporphyrinogen IX.
EINECS	Contact for details

Quality Control

Our Harderoporphyrinogen is produced and handled under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and diagnostic applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous in-house standards aligned with general principles of Good Manufacturing Practice (GMP) for fine chemicals. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. The product is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light brown powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in alkaline aqueous solutions, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.