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1,2-Dilauroyl-Sn-Glycero-3-Phosphatidylethanolamine CAS NO 42436-56-6


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CAS No.:42436-56-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-Dilauroyl-Sn-Glycero-3-Phosphatidylethanolamine is a synthetic, saturated phospholipid belonging to the phosphatidylethanolamine (PE) class, widely recognized for its role as a key structural and functional component in lipid-based formulations. This high-purity compound is essential for creating stable, biocompatible lipid bilayers and vesicles, making it a critical material for advanced research and pharmaceutical development. It is primarily utilized by scientists and manufacturers in the life sciences, drug delivery, and cosmetic industries for applications requiring precise membrane modeling and encapsulation.

Application

  • Liposome and Nanoparticle Formulation: A fundamental building block for constructing liposomal drug delivery systems, mRNA-LNPs (lipid nanoparticles), and other nanocarriers for targeted therapy.
  • Membrane Biophysics Research: Used as a model phospholipid to study membrane fluidity, phase behavior, and protein-lipid interactions in controlled experimental settings.
  • Biomimetic Coatings & Sensors: Employed in creating supported lipid bilayers (SLBs) for biosensor development, surface modification, and cell membrane mimicry.
  • Cosmetic & Dermal Delivery Systems: Incorporated into topical formulations and cosmetic products as an emulsifier and penetration enhancer for active ingredients.
  • Cell Culture & Cryopreservation: Acts as a supplement in specialized cell culture media and as a protective agent in cryopreservation solutions.
  • Diagnostic Reagent Preparation: Serves as a raw material in the preparation of diagnostic kits and reagents that rely on lipid membrane structures.

Basic Information

Product Name 1,2-Dilauroyl-Sn-Glycero-3-Phosphatidylethanolamine
CAS No. 42436-56-6
Molecular Formula C31H62NO8P
Molecular Weight 607.79 g/mol
Synonyms DLPE; 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine; Dilauroylphosphatidylethanolamine; PE(12:0/12:0); 1,2-Didodecanoyl-sn-glycero-3-phosphoethanolamine; L-α-Phosphatidylethanolamine, dilauroyl; 3-sn-Phosphatidylethanolamine, 1,2-didodecanoyl; Lauryl PE
EINECS Contact for details

Quality Control

Every batch of our 1,2-Dilauroyl-Sn-Glycero-3-Phosphatidylethanolamine is manufactured and analyzed under strict quality management systems to ensure exceptional purity and batch-to-batch consistency suitable for research and GMP-grade applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, purity, and impurity profiles. Our quality commitment aligns with the stringent requirements of pharmaceutical excipient and advanced material supply.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. This material is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed container to equilibrate to room temperature before opening to prevent condensation. For long-term stability, store desiccated.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Melting Point Contact for details
Heavy Metals ≤ 10 ppm
Residual Solvents (GC) Meets ICH guidelines
Microbial Limits Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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