Description

2-Nor-2-Formylpyridoxal-5'-Phosphate is a chemically modified derivative of pyridoxal 5'-phosphate (PLP), the active coenzyme form of vitamin B6. This compound is of significant interest in biochemical research and pharmaceutical development due to its role as a potential enzyme inhibitor and a versatile synthetic intermediate for probing PLP-dependent enzymatic mechanisms. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on enzymology, metabolic pathway analysis, and novel therapeutic agent synthesis.

Application

• Biochemical Research: Used as a tool compound and a synthetic precursor in the study of PLP-dependent enzymes, such as transaminases, decarboxylases, and racemases.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of novel drug candidates targeting metabolic disorders and neurological conditions.
• Enzyme Inhibition Studies: Acts as a potential inhibitor to investigate enzyme kinetics, active site architecture, and catalytic mechanisms in vitamin B6-dependent systems.
• Diagnostic Reagent Development: Employed in the formulation of specialized reagents for clinical diagnostics and research assay kits.
• Academic & Industrial R&D: Essential for fundamental research in universities and applied research in biotechnology companies exploring coenzyme analogs.

Basic Information

Product Name	2-Nor-2-Formylpyridoxal-5'-Phosphate
CAS No.	42253-87-2
Molecular Formula	C11H12NO8P
Molecular Weight	317.19 g/mol
Synonyms	2-Formyl-3-hydroxy-5-(hydroxymethyl)-4-methylpyridine 4-(Dihydrogen phosphate); 2-Nor-2-formyl-PLP; 2-Formylpyridoxal phosphate; PLP analog; Pyridoxal phosphate derivative; Vitamin B6 coenzyme analog; 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 4-phosphate
EINECS	Contact for details

Quality Control

Our 2-Nor-2-Formylpyridoxal-5'-Phosphate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.