Description

Estriol 17-Sulfate is a sulfated metabolite of the natural estrogen estriol, characterized by its specific conjugation at the 17-position. This compound is of significant value as a critical reference standard and biochemical intermediate for research and diagnostic applications. It is primarily needed by pharmaceutical R&D laboratories, clinical diagnostics manufacturers, and academic institutions focusing on endocrinology, hormone metabolism, and biomarker discovery.

Application

• Pharmaceutical Reference Standard: Used for the quantification and qualification of estriol metabolites in drug development and bioanalytical method validation.
• Clinical Diagnostics: Serves as a calibrator or control in immunoassays and LC-MS/MS kits for measuring estrogen levels in serum, plasma, or urine.
• Biochemical Research: Employed in studies investigating estrogen sulfation pathways, enzyme kinetics of sulfotransferases, and hormone conjugation mechanisms.
• Metabolite Identification: A key analyte in mass spectrometry-based metabolomics and pharmacokinetic studies to identify and track estrogen-derived metabolites.
• Endocrinology Studies: Used in research models to understand the role of sulfated hormones in pregnancy, fetal development, and endocrine-related conditions.

Basic Information

Product Name	Estriol 17-Sulfate
CAS No.	42028-21-7
Molecular Formula	C18H22O6S
Molecular Weight	366.43 g/mol
Synonyms	Estriol 17-Sulfate; Estriol 17-(Hydrogen Sulfate); 16α-Hydroxyestriol 17-Sulfate; Estr-5(10)-ene-3,16α,17β-triol 17-Sulfate; 3,16α-Dihydroxy-17β-sulfooxyestra-1,3,5(10)-triene; Estriol 17-Monosulfate; 17β-Sulfooxyestra-1,3,5(10)-triene-3,16α-diol
EINECS	Contact for details

Quality Control

Our Estriol 17-Sulfate is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and diagnostic use. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.