Description

1α-Methoxycrinan is a specialized alkaloid derivative with a defined crinane skeleton. This compound is valued for its role as a key synthetic intermediate and reference standard in advanced organic chemistry and pharmaceutical research. It is primarily utilized by research institutions and chemical manufacturers engaged in the development of novel bioactive molecules and complex natural product syntheses.

Application

• Pharmaceutical Research Intermediate: Serves as a crucial building block in the synthesis of novel alkaloid-based drug candidates and pharmacologically active compounds.
• Reference Standard: Used as a high-purity analytical standard for method development, quality control, and identification in chromatographic analysis (HPLC, GC-MS).
• Natural Product Synthesis: A key precursor in the total or semi-synthesis of complex Amaryllidaceae alkaloids and related natural products.
• Biochemical Research: Employed in studies investigating structure-activity relationships (SAR) and the biological pathways of crinane-type alkaloids.
• Chemical Library Development: Used to create focused libraries of structurally related analogs for high-throughput screening in drug discovery programs.

Basic Information

Product Name	1α-Methoxycrinan
CAS No.	41928-92-1
Molecular Formula	C17H21NO3
Molecular Weight	287.35 g/mol
Synonyms	1α-Methoxycrinan; 1-Methoxycrinan; Crinan, 1-methoxy-; 1α-Methoxycrinane; 1-Methoxy-9,10-didehydro-6-methyl-2H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridin-2-ol (related IUPAC forms); Contact for additional aliases.
EINECS	Contact for details

Quality Control

Our 1α-Methoxycrinan is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom purity grades and analytical packages are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). For long-term storage, consider storing under inert atmosphere at lower temperatures (-20°C) to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.