Description

10-Hydroxyyohimbine is a significant indole alkaloid derivative, recognized for its role as a key intermediate and reference standard in advanced research and development. This compound is valued for its structural specificity, enabling precise pharmacological and biochemical studies. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for the synthesis of novel compounds and as a critical analytical standard.

Application

• Pharmaceutical Research & Development: Serves as a crucial intermediate in the synthesis of novel therapeutic agents targeting neurological and metabolic pathways.
• Reference Standard: Used as a high-purity analytical standard in HPLC, LC-MS, and other chromatographic methods for method development, validation, and quality control.
• Biochemical Research: Employed in in vitro studies to investigate receptor binding affinity, enzyme inhibition, and other mechanistic actions related to its parent alkaloid class.
• Academic Studies: A key compound for structural-activity relationship (SAR) studies and for teaching advanced organic chemistry and pharmacology.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific indole alkaloid frameworks.

Basic Information

Product Name	10-Hydroxyyohimbine
CAS No.	41928-02-3
Molecular Formula	C21H26N2O4
Molecular Weight	370.45 g/mol
Synonyms	10-Hydroxyyohimbine; 10α-Hydroxyyohimbine; 17α-Hydroxyyohimban-16α-carboxylic acid methyl ester; 10-Hydroxy-17α-hydroxyyohimban-16α-carboxylic acid methyl ester; Rauwolscine 10-ol; Corynanthine derivative
EINECS	Contact for details

Quality Control

Our 10-Hydroxyyohimbine is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability, consistency, and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.