Description

(20α)-3,5,6,16,17-Pentadehydro-10,11-Dimethoxy-16-(Methoxycarbonyl)-19α-Methyl-18-Oxayohimban-4-Ium is a complex indole alkaloid derivative, a key intermediate in advanced pharmaceutical synthesis. This compound matters for its role as a critical building block in the research and development of novel therapeutic agents, particularly within the central nervous system and cardiovascular domains. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex alkaloid-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies and the development of new drug candidates targeting specific receptors.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Process Development: Employed in the optimization and scale-up of synthetic routes for complex organic molecules in pilot plants.
• Biochemical Research: Utilized in studies investigating the biological activity and mechanism of action of yohimbane-related alkaloids.

Basic Information

Product Name	(20α)-3,5,6,16,17-Pentadehydro-10,11-Dimethoxy-16-(Methoxycarbonyl)-19α-Methyl-18-Oxayohimban-4-Ium
CAS No.	41758-43-4
Molecular Formula	C23H24N2O5+
Molecular Weight	408.45 g/mol
Synonyms	10,11-Dimethoxy-16-(methoxycarbonyl)-19α-methyl-18-oxayohimban-4-ium; 3,5,6,16,17-Pentadehydro-10,11-dimethoxy-16-(methoxycarbonyl)-19α-methyl-18-oxayohimban-4-ium; Methyl 10,11-dimethoxy-19α-methyl-4,18-didehydro-18-oxayohimban-16-carboxylate cation; Yohimbane alkaloid derivative; Oxayohimbanium salt.
EINECS	Contact for details

Quality Control

Our (20α)-3,5,6,16,17-Pentadehydro-10,11-Dimethoxy-16-(Methoxycarbonyl)-19α-Methyl-18-Oxayohimban-4-Ium is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). Certificates of Analysis (COA) detailing batch-specific results are provided to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.