Description

Latanoprost Acid CAS NO 41639-83-2 is a key pharmaceutical intermediate and the active carboxylic acid form of the prostaglandin analog Latanoprost. This compound is of critical importance for the synthesis of high-purity, ophthalmic-grade active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical manufacturers and advanced research facilities engaged in the development and production of glaucoma and ocular hypertension treatments.

Application

• Primary Pharmaceutical Intermediate: The essential building block for the synthesis of Latanoprost API, a first-line medication for reducing intraocular pressure.
• Ophthalmic Drug Manufacturing: Serves as the core starting material in GMP-compliant production lines for anti-glaucoma eye drops and solutions.
• Research & Development (R&D): Used in pharmaceutical R&D for developing novel prostaglandin-based therapeutics and studying structure-activity relationships.
• Analytical Reference Standard: Employed as a high-purity reference standard in quality control laboratories for HPLC, LC-MS, and other analytical methods.
• Process Development & Scale-up: Critical for process chemistry teams optimizing synthetic routes and scaling up production from lab to commercial batch sizes.
• Generic Drug Formulation: A vital raw material for manufacturers producing generic versions of prostaglandin analog medications.

Basic Information

Product Name	Latanoprost Acid
CAS No.	41639-83-2
Molecular Formula	C₂₆H₄₀O₅
Molecular Weight	432.59 g/mol
Synonyms	Latanoprost Free Acid; (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoic Acid; 13,14-Dihydro-17-phenyl-18,19,20-trinor-PGF2α-isopropyl Ester Acid; PhXA-85; Prostaglandin F2α analog acid; Isopropyl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoate acid
EINECS	Contact for details

Quality Control

Our Latanoprost Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards suitable for pharmaceutical synthesis. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, supporting regulatory filings and GMP compliance for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.