Description

D-Galactosyl-β1,1' N-Lauroyl-D-Erythro-Sphingosine is a chemically defined, high-purity glycosphingolipid derivative, specifically a galactosylceramide with a lauroyl fatty acid chain. This compound is a critical biochemical tool and a key intermediate for advanced research in immunology, cell biology, and lipidomics. It is essential for scientists and manufacturers developing novel therapeutics, diagnostic reagents, and studying lipid raft dynamics, membrane signaling, and autoimmune disorders. The product is supplied under stringent quality control to ensure batch-to-batch consistency for reliable experimental and production outcomes.

Application

• Biochemical Research: A key standard and substrate for studying glycosphingolipid metabolism, enzyme kinetics (e.g., galactocerebrosidase activity), and lipid-protein interactions.
• Pharmaceutical Development: Serves as a critical intermediate or reference compound in the synthesis of novel drug candidates targeting neurological diseases, lysosomal storage disorders, and immune modulation.
• Diagnostic Reagent Manufacturing: Used in the production of high-specificity assay kits, antibodies, and probes for detecting lipid antigens and related biomarkers.
• Cell Biology & Immunology: Employed to modulate cell membrane structure, investigate lipid raft formation, and study immune cell activation and antigen presentation pathways.
• Lipidomics & Metabolomics: An essential analytical standard for the accurate identification and quantification of complex sphingolipids in biological samples using LC-MS/MS and other advanced techniques.
• Neuroscience Research: Applied in studies of myelin formation, neuronal development, and the pathophysiology of diseases like multiple sclerosis and Krabbe disease.

Basic Information

Product Name	D-Galactosyl-β1,1' N-Lauroyl-D-Erythro-Sphingosine
CAS No.	41613-14-3
Molecular Formula	C36H69NO8
Molecular Weight	643.94 g/mol
Synonyms	N-Lauroyl-D-erythro-sphingosyl-1-O-β-D-galactopyranoside; Galactosylceramide (C12:0); β-D-Galactosyl-N-lauroylsphingosine; D-Galactosyl-β1,1' N-Dodecanoylsphingosine; GalCer (C12); N-Lauroylpsychosine; Lactosylceramide analog (C12); Glycosphingolipid (d12:0/18:1)
EINECS	Contact for details

Quality Control

Our D-Galactosyl-β1,1' N-Lauroyl-D-Erythro-Sphingosine is manufactured under controlled conditions to meet the exacting standards of research and pharmaceutical applications. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to confirm identity, purity, and structural integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 2.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.