Description

4,R-Ajmalicine n-Oxide is a specialized alkaloid derivative, a key intermediate in the synthesis of complex pharmaceutical compounds. Its value lies in its specific stereochemistry and functional group, which are critical for producing targeted bioactive molecules. This high-purity intermediate is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical synthesis facilities focused on developing new therapeutic agents, particularly in the areas of neurological and cardiovascular research.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).
• Neurological Research: Used in the development and study of compounds targeting specific neurological pathways.
• Cardiovascular Drug Development: Serves as a precursor in the synthesis of potential cardiovascular therapeutic agents.
• Alkaloid Chemistry Research: A valuable reference standard and starting material for academic and industrial research into indole alkaloids and their derivatives.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes and scaling up production for clinical trial material.
• Biochemical Tool Compound: Used in vitro to study enzyme interactions and receptor binding activities.

Basic Information

Product Name	4,R-Ajmalicine n-Oxide
CAS No.	41590-29-8
Molecular Formula	C21H24N2O4
Molecular Weight	368.43 g/mol
Synonyms	Ajmalicine N-Oxide; 19α(S)-Ajmalicine Nb-Oxide; (19S)-Ajmalicine N-Oxide; 4,R-Ajmalicine N-Oxide; 19-Epi-ajmalicine N-Oxide; Raubasine N-Oxide; δ-Yohimbine N-Oxide
EINECS	Contact for details

Quality Control

Every batch of 4,R-Ajmalicine n-Oxide is produced and tested under a strict quality management system to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for all critical parameters including assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.