Description

Gelsemine, 18,19-Dihydro-1-Methoxy- CAS NO 41478-35-7 is a high-purity alkaloid derivative, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its specific structural modifications, which are critical for studying structure-activity relationships and developing novel therapeutic agents. It is primarily sought by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in neuropharmacology, medicinal chemistry, and the synthesis of complex natural product analogs.

Application

• Pharmaceutical Research & Development: A crucial reference standard and building block for the synthesis of novel bioactive compounds targeting neurological pathways.
• Medicinal Chemistry: Used in lead optimization and structure-activity relationship (SAR) studies due to its specific alkaloid scaffold.
• Academic & Institutional Research: Serves as a key reagent in pharmacological studies investigating alkaloid effects and mechanisms of action.
• Fine Chemical Synthesis: An important intermediate for the custom synthesis of specialized alkaloid derivatives and analogs.
• Analytical Standard: Employed as a high-purity standard in HPLC, LC-MS, and NMR for method development, validation, and quality control in related product analysis.

Basic Information

Product Name	Gelsemine, 18,19-Dihydro-1-Methoxy-
CAS No.	41478-35-7
Molecular Formula	C21H24N2O3
Molecular Weight	352.43 g/mol
Synonyms	1-Methoxy-18,19-dihydrogelsemine; 18,19-Dihydro-1-methoxygelsemine; Dihydro-1-methoxygelsemine; Gelsemine derivative; (3β,5β,16S)-1-Methoxy-18,19-dihydrogelsemine; 1-Methoxy-18,19-dihydrogelsemine (CAS 41478-35-7); 18,19-Dihydro-1-methoxy-gelsemine
EINECS	Contact for details

Quality Control

Our Gelsemine, 18,19-Dihydro-1-Methoxy- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for your quality assurance records.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.