Description

(+/-)-Anabasine CAS NO 40774-73-0 is a naturally occurring alkaloid and a structural analog of nicotine, known for its potent nicotinic acetylcholine receptor (nAChR) agonist activity. This compound serves as a critical research-grade biochemical for pharmacological and neurological studies, providing insights into receptor function and signaling pathways. It is essential for academic research institutions, pharmaceutical R&D laboratories, and agrochemical developers engaged in neuroscience, toxicology, and the development of novel therapeutic or pest control agents.

Application

• Neuroscience Research: Used as a selective tool compound to study nicotinic acetylcholine receptor (nAChR) subtypes, their distribution, and physiological roles in the central and peripheral nervous systems.
• Pharmacological Profiling: Employed in in vitro and in vivo assays to investigate agonist/antagonist effects, receptor desensitization, and structure-activity relationships (SAR) for drug discovery.
• Toxicology Studies: Serves as a reference standard in metabolic and toxicokinetic studies due to its biological activity and presence in certain plants.
• Agrochemical Research: Investigated for its potential as a lead compound or analog in the development of novel, selective insecticides and pest management agents.
• Chemical Synthesis: Acts as a key chiral intermediate or building block for the synthesis of more complex alkaloids and specialized pharmaceutical candidates.
• Analytical Reference Standard: Provides a high-purity standard for quality control and method validation in analytical laboratories using techniques like HPLC, GC-MS, or LC-MS.

Basic Information

Product Name	(+/-)-Anabasine
CAS No.	40774-73-0
Molecular Formula	C10H14N2
Molecular Weight	162.23 g/mol
Synonyms	Anabasine (racemic); DL-Anabasine; 3-(2-Piperidinyl)pyridine; Neonicotine; 2-(3-Pyridyl)piperidine; (RS)-Anabasine; (±)-Anabasine; 1,2,3,4,5,6-Hexahydro-2,3'-bipyridine
EINECS	Contact for details

Quality Control

Our (+/-)-Anabasine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity determination by chromatographic techniques. A Certificate of Analysis (COA) detailing specific results for purity, residual solvents, and other critical parameters is provided with every shipment to support your compliance and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider sealing under an inert gas such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.