Description

D-Glucose-1-13C is a stable isotope-labeled analog of D-glucose, where the carbon atom at the 1-position is enriched with the non-radioactive carbon-13 isotope. This product is essential for advanced metabolic research, enabling precise tracking and quantification of glucose utilization and metabolic flux in biological systems. It is a critical reagent for scientists and manufacturers in pharmaceutical R&D, clinical diagnostics, and academic research focused on metabolism, diabetes, and cancer biology.

Application

• Metabolic Flux Analysis (MFA): Used as a tracer to map intracellular metabolic pathways and quantify reaction rates in cell cultures, tissues, and microorganisms.
• Pharmaceutical Research & Development: Employed in drug discovery to study the effects of new compounds on glucose metabolism, particularly in oncology and metabolic disease models.
• Clinical Diagnostic Assays: Serves as an internal standard in mass spectrometry-based assays (e.g., LC-MS/MS) for the accurate quantification of glucose and related metabolites in biological fluids.
• Nutritional Science Studies: Facilitates research into carbohydrate metabolism, energy expenditure, and substrate utilization in both human and animal studies.
• Biochemical Research: A key tool for enzymology studies, investigating the mechanisms of glycolytic and gluconeogenic enzymes.
• Isotope-Labeled Standard Production: Used as a precursor for the synthesis of more complex carbon-13 labeled compounds for research and diagnostic purposes.

Basic Information

Product Name	D-Glucose-1-13C
CAS No.	40762-22-9
Molecular Formula	C512C13H12O6
Molecular Weight	181.15 g/mol
Synonyms	1-13C-Glucose; D-(+)-Glucose-1-13C; Glucose-1-13C; Dextrose-1-13C; (2R,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanal-1-13C; D-Glucose (1-13C); 13C1-Glucose; Isotopically Labeled D-Glucose
EINECS	Contact for details

Quality Control

Our D-Glucose-1-13C is produced and tested under stringent quality management systems. Each batch is characterized to ensure high chemical and isotopic purity, with critical parameters including isotopic enrichment (atom % 13C), chemical purity (HPLC), and specific optical rotation verified. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Specific Optical Rotation	+52.5° to +53.0° (c=10 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.