Description

(R)-(-)-1-Phenyl-1,2-Ethanediol 2-Tosylate CAS NO 40434-87-5 is a high-purity chiral building block and synthetic intermediate. This compound is of significant value for the stereoselective synthesis of complex molecules, particularly in the pharmaceutical sector. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing active pharmaceutical ingredients (APIs) and other high-value chiral compounds.

Application

• Chiral Synthesis: A key intermediate in the asymmetric synthesis of pharmaceuticals, including β-blockers and other cardiovascular agents.
• Pharmaceutical Research: Used in medicinal chemistry for the development and scale-up of enantiomerically pure drug candidates.
• Agrochemical Development: Serves as a precursor in the synthesis of chiral pesticides and herbicides.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Process Chemistry: A valuable reagent for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	(R)-(-)-1-Phenyl-1,2-Ethanediol 2-Tosylate
CAS No.	40434-87-5
Molecular Formula	C15H16O4S
Molecular Weight	292.35 g/mol
Synonyms	(R)-(-)-1-Phenylethane-1,2-diol 2-Tosylate; (R)-Styrene Glycol 2-Tosylate; (1R)-1-Phenyl-1,2-ethanediol 2-(4-methylbenzenesulfonate); (R)-1-Phenyl-2-[(4-methylphenyl)sulfonyl]oxy]ethanol; (R)-1-Phenylethane-1,2-diyl bis(4-methylbenzenesulfonate) (for the ditosylate derivative, commonly referenced); (R)-Hydrobenzoin 2-Tosylate; (R)-1,2-Dihydroxy-1-phenylethane 2-Tosylate
EINECS	Contact for details

Quality Control

Our (R)-(-)-1-Phenyl-1,2-Ethanediol 2-Tosylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.