Description

2-Chlorobenzylmercapturic Acid is a specific and stable mercapturic acid metabolite, serving as a critical biomarker for exposure to certain industrial chemicals and environmental pollutants. Its high purity and structural integrity make it an essential reference standard for analytical and diagnostic applications. This compound is primarily required by research institutions, contract research organizations (CROs), and analytical laboratories engaged in toxicology studies, biomonitoring, and metabolic pathway research.

Application

• Biomarker Reference Standard: Used as a certified reference material (CRM) for the quantification of human exposure to chlorinated aromatic compounds in occupational and environmental health studies.
• Toxicology & Metabolism Research: Essential for studying the metabolic pathways, specifically the glutathione conjugation (Phase II metabolism), of 2-chlorobenzyl chloride and related compounds.
• Analytical Method Development: Serves as a primary standard for calibrating analytical instruments such as LC-MS/MS, HPLC, and GC-MS in method validation for biological matrices.
• Clinical & Forensic Analysis: Employed in laboratories performing biomonitoring to assess exposure levels in urine or blood samples for health risk assessments.
• Pharmaceutical Impurity Profiling: Can be utilized in the development and validation of methods to trace and quantify potential mercapturate-related impurities in drug substances.
• Regulatory Compliance Testing: Supports testing protocols to meet occupational safety and environmental regulatory requirements by providing a reliable analytical benchmark.

Basic Information

Item	Detail
Product Name	2-Chlorobenzylmercapturic Acid
CAS No.	40379-72-4
Molecular Formula	C12H14ClNO4S
Molecular Weight	303.76 g/mol
Synonyms	N-Acetyl-S-(2-chlorobenzyl)-L-cysteine; 2-Chlorobenzylmercapturic Acid; (2R)-2-Acetamido-3-[(2-chlorophenyl)methylsulfanyl]propanoic Acid; S-(2-Chlorobenzyl)-N-acetylcysteine; 2-Chloro-α-methylbenzylmercapturic Acid; Mercapturic Acid, 2-Chlorobenzyl-; N-Acetyl-S-(2-chlorobenzyl)cysteine
EINECS	Contact for details

Quality Control

Every batch of 2-Chlorobenzylmercapturic Acid is produced and controlled under a strict quality management system. We employ advanced chromatographic techniques (HPLC, LC-MS) to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.