Description

(R)-1,2-Butanediol is a high-purity, chiral diol and a valuable building block in fine chemical synthesis. Its stereochemical purity makes it a critical intermediate for producing optically active pharmaceuticals, agrochemicals, and advanced materials. This compound is essential for research and manufacturing in the pharmaceutical, flavor & fragrance, and specialty polymer industries where precise molecular configuration dictates product performance.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral and cardiovascular drugs.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Flavor and Fragrance Ingredient: Serves as a precursor for lactones and other compounds that impart specific flavor and aroma profiles.
• Polymer Modifier: Incorporated into specialty polyesters and polyurethanes to influence crystallinity, flexibility, and biodegradability.
• Asymmetric Catalyst Ligand: Utilized in the development of chiral ligands for metal-catalyzed asymmetric reactions.
• Cosmetic Formulations: Acts as a humectant and solvent in high-end cosmetic and personal care products.
• Research & Development: A standard reagent in organic chemistry laboratories for method development and chiral studies.

Basic Information

Product Name	(R)-1,2-Butanediol
CAS No.	40348-66-1
Molecular Formula	C4H10O2
Molecular Weight	90.12 g/mol
Synonyms	(R)-(+)-1,2-Butanediol; (R)-1,2-Dihydroxybutane; D-(-)-1,2-Butanediol; (2R)-Butane-1,2-diol; (R)-Butylene Glycol; (R)-1,2-Butylene Glycol; (R)-1,2-BD
EINECS	254-896-5

Quality Control

Our (R)-1,2-Butanediol is manufactured under strict quality management systems. Each batch is tested to ensure high chemical and enantiomeric purity, meeting the stringent requirements for chiral intermediates. Certificates of Analysis (COA) detailing specific parameters such as assay, enantiomeric excess (ee), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Specific Rotation [α]20/D	+13.5° to +15.0° (c=1 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.