Description

Eburnamenine-14-Carboxylic Acid, 14,15-Dihydro-14-Hydroxy-, Ethyl Ester, (3A,14B,16A)- is a high-purity, complex alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for synthesizing novel therapeutic agents targeting neurological and cardiovascular systems. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of nootropic and vasodilatory drugs. Our supply is characterized by stringent quality control, ensuring batch-to-batch consistency for reliable experimental and process-scale outcomes.

Application

• Pharmaceutical Intermediate: Key building block in the synthetic pathway for Vincamine and related Eburnamine alkaloid derivatives.
• Reference Standard: High-purity material for analytical method development, validation, and quality control in pharmaceutical manufacturing.
• Neurological Research: Used in preclinical studies investigating compounds for cognitive enhancement, cerebral vasodilation, and neuroprotection.
• Active Pharmaceutical Ingredient (API) Synthesis: Intermediate in the production of APIs for medications intended to improve cerebral metabolism and blood flow.
• Chemical Biology: Probe molecule for studying biological pathways and receptor interactions related to its pharmacological activity.
• Process Chemistry Development: Serves as a model compound for optimizing stereoselective synthesis and purification techniques in fine chemical production.

Basic Information

Product Name	Eburnamenine-14-Carboxylic Acid, 14,15-Dihydro-14-Hydroxy-, Ethyl Ester, (3A,14B,16A)-
CAS No.	40163-56-2
Molecular Formula	C21H26N2O3
Molecular Weight	354.45 g/mol
Synonyms	14-Hydroxy-14,15-dihydroeburnamenine-14-carboxylic acid ethyl ester; Ethyl (3α,14β,16α)-14,15-dihydro-14-hydroxyeburnamenine-14-carboxylate; Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-, ethyl ester, (3α,14β,16α)-; Vincamine intermediate; Apovincaminic acid ethyl ester derivative; (3α,14β,16α)-14-Hydroxy-14,15-dihydroeburnamenine-14-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Eburnamenine-14-Carboxylic Acid, 14,15-Dihydro-14-Hydroxy-, Ethyl Ester, (3A,14B,16A)- is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.