Description

(2α,17S,19E)-1-Acetyl-19,20-Didehydro-1-Demethyl-17-(Acetyloxy)Ajmalan-16-Carboxylic Acid Methyl Ester is a high-purity, semi-synthetic alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of complex bioactive molecules, particularly in the exploration of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex alkaloid-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic compounds with potential neurological or cardiovascular activity.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating the biological activity and metabolic pathways of ajmalan-type alkaloids.
• Process Development: Used for scaling up and optimizing synthetic routes in pilot plants and commercial manufacturing settings.
• Academic Research: A valuable compound for universities and research institutes studying natural product chemistry and organic synthesis.

Basic Information

Product Name	(2α,17S,19E)-1-Acetyl-19,20-Didehydro-1-Demethyl-17-(Acetyloxy)Ajmalan-16-Carboxylic Acid Methyl Ester
CAS No.	4914-01-6
Molecular Formula	C25H30N2O5
Molecular Weight	438.52 g/mol
Synonyms	1-Acetyl-19,20-didehydro-1-demethyl-17-(acetyloxy)ajmalan-16-carboxylic acid methyl ester; Methyl (2α,17S,19E)-1-acetyl-19,20-didehydro-1-demethyl-17-(acetyloxy)ajmalan-16-carboxylate; Ajmaline derivative; 17-Acetoxy-1-acetyl-19,20-didehydro-1-demethylajmalan-16-methyl carboxylate; 1-Demethyl-1-acetyl-17-acetoxy-19,20-didehydroajmalan-16-methyl ester
EINECS	Contact for details

Quality Control

Our (2α,17S,19E)-1-Acetyl-19,20-Didehydro-1-Demethyl-17-(Acetyloxy)Ajmalan-16-Carboxylic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.