Description

(-)-Eburnamonine is a naturally occurring indole alkaloid of significant pharmaceutical interest. This compound serves as a key intermediate and reference standard in the research and development of neurological and cardiovascular therapeutics. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of fine chemicals and active pharmaceutical ingredients (APIs). The compound's defined stereochemistry is critical for its biological activity and research applications.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of more complex alkaloids and potential drug candidates targeting neurological pathways.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical laboratories to ensure product purity and identity.
• Biochemical Research: Employed in pharmacological studies to investigate its effects on vasodilation, cerebral blood flow, and neuronal function.
• Natural Product Chemistry: Serves as a model compound in the study of indole alkaloid biosynthesis, extraction, and isolation techniques.
• Fine Chemical Synthesis: Utilized in asymmetric synthesis and chiral chemistry research due to its specific stereochemical configuration.

Basic Information

Product Name	(-)-Eburnamonine
CAS No.	4880-88-0
Molecular Formula	C19H22N2O
Molecular Weight	294.39 g/mol
Synonyms	(-)-Eburnamonine; Eburnamonine; (3S,15S,16S)-Eburnamonine; (15S,16S)-Eburnamonine; Vincamajoridine; Lewen; Cebranic; Eburnamenine-14-carboxylic acid, methyl ester, (14beta)-; Methyl (14beta)-eburnamenine-14-carboxylate
EINECS	Contact for details

Quality Control

Our (-)-Eburnamonine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identification via IR and NMR spectroscopy. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with cGMP and ICH guidelines for pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.