Description

5-Diphosphomevalonic Acid is a key phosphorylated intermediate in the mevalonate pathway, essential for the biosynthesis of isoprenoids and sterols. This high-purity biochemical is critical for research and development in metabolic studies and enzyme kinetics. It serves as a vital reagent for pharmaceutical researchers, biochemists, and manufacturers in the life sciences sector investigating cholesterol synthesis, terpene production, and related metabolic disorders.

Application

• Biochemical Research: Used as a high-purity substrate for studying the enzymatic activity of mevalonate kinase and phosphomevalonate kinase.
• Metabolic Pathway Analysis: Essential for in vitro experiments modeling the mevalonate pathway to understand isoprenoid biosynthesis.
• Pharmaceutical Development: Serves as a reference standard and intermediate in drug discovery programs targeting cholesterol-lowering agents and diseases related to isoprenoid metabolism.
• Enzyme Inhibition Studies: Utilized to screen and characterize potential inhibitors of enzymes in the sterol synthesis pathway.
• Academic & Institutional Labs: A fundamental reagent for graduate-level and post-doctoral research in biochemistry and molecular biology.
• Diagnostic Kit Manufacturing: May be incorporated as a component in enzymatic assay kits for clinical research and diagnostic purposes.

Basic Information

Product Name	5-Diphosphomevalonic Acid
CAS No.	4872-34-8
Molecular Formula	C6H16O13P2
Molecular Weight	358.13 g/mol
Synonyms	Mevalonic Acid 5-Diphosphate; Mevalonate 5-Diphosphate; 5-Diphosphomevalonate; (R)-5-Diphosphomevalonic Acid; 3,5-Dihydroxy-3-methylpentanoic Acid 5-Diphosphate; MVA-5-PP; Phosphomevalonic Acid Diphosphate
EINECS	Contact for details

Quality Control

Our 5-Diphosphomevalonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.