Description

(4α,20S)-20-Hydroxyibogamine-18-Carboxylic Acid Methyl Ester is a high-purity, semi-synthetic iboga alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate and reference standard for the synthesis and study of novel therapeutic agents targeting neurological pathways. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of central nervous system (CNS) drugs and neuropharmacological studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex alkaloid-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in laboratories.
• Neuroscience Research: Employed in preclinical studies to investigate receptor interactions and mechanisms of action related to iboga alkaloids.
• Process Chemistry: Serves as a starting material or intermediate in scale-up processes for the production of specialized fine chemicals.
• Academic Research: Utilized in university and institutional labs for chemical synthesis projects and pharmacological profiling.

Basic Information

Product Name	(4α,20S)-20-Hydroxyibogamine-18-Carboxylic Acid Methyl Ester
CAS No.	4865-78-5
Molecular Formula	C21H26N2O3
Molecular Weight	354.45 g/mol
Synonyms	20-Hydroxyibogamine-18-carboxylic acid methyl ester; Methyl 20-hydroxyibogamine-18-carboxylate; 18-Methoxycarbonyl-20-hydroxyibogamine; Ibogaine derivative; 4865-78-5; (4a,20S)-20-Hydroxyibogamine-18-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our (4α,20S)-20-Hydroxyibogamine-18-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and detailed Certificates of Analysis (COA) to support your research and regulatory requirements, ensuring compliance with internal specifications suitable for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as argon or nitrogen to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.