Description

(R)-Nornuciferine is a chiral isoquinoline alkaloid of significant interest in advanced chemical synthesis and pharmaceutical research. This compound serves as a key intermediate and a valuable reference standard for the development of novel bioactive molecules. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers focused on neuroscience, metabolic studies, and asymmetric synthesis.

Application

• Pharmaceutical Reference Standard: Used as a high-purity analytical standard for quality control and method development in drug discovery pipelines.
• Biochemical Research: Employed in pharmacological studies to investigate interactions with neurotransmitter receptors and metabolic pathways.
• Asymmetric Synthesis Intermediate: Serves as a chiral building block for the synthesis of more complex natural product analogs and potential therapeutic agents.
• Neuroscience Research: Utilized as a tool compound in vitro and in vivo to study its effects on the central nervous system.
• Analytical Method Development: Acts as a critical component for developing and validating chromatographic methods (e.g., HPLC, LC-MS) for alkaloid analysis.

Basic Information

Product Name	(R)-Nornuciferine
CAS No.	4846-19-9
Molecular Formula	C₁₈H₁₉NO₂
Molecular Weight	281.35 g/mol
Synonyms	(R)-Nornuciferine; (R)-5,6,6a,7-Tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinoline; (R)-1,2,10-Trimethoxyaporphine; (R)-Nornuciferin; R-Nornuciferine; (-)-Nornuciferine; Nornuciferine R-isomer
EINECS	Contact for details

Quality Control

Our (R)-Nornuciferine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for reference materials, ensuring reliable and reproducible performance in your laboratory.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.