Description

S-Phenylmercapturic Acid is a specific and stable urinary metabolite of benzene, widely used as a critical biomarker in occupational and environmental health studies. Its reliable detection is essential for accurate biological monitoring of benzene exposure, a known human carcinogen. This high-purity reference standard is indispensable for analytical laboratories in toxicology, industrial hygiene, and pharmaceutical research, ensuring precise calibration and validation of analytical methods.

Application

• Biomarker for Benzene Exposure: Primary application as a specific, sensitive urinary biomarker for monitoring occupational and environmental exposure to benzene.
• Toxicology and Risk Assessment: Used in research and regulatory studies to assess health risks associated with benzene and to establish biological exposure indices (BEIs).
• Clinical and Occupational Health: Essential for biological monitoring programs in industries such as petrochemicals, rubber manufacturing, and fuel handling.
• Analytical Reference Standard: Serves as a certified reference material (CRM) for calibrating equipment like LC-MS/MS, HPLC, and GC-MS in analytical laboratories.
• Metabolic Pathway Studies: Utilized in pharmacological and biochemical research to study the metabolic fate and detoxification pathways of aromatic compounds.
• Method Development and Validation: Critical for developing, validating, and ensuring the accuracy of bioanalytical methods in compliance with GLP guidelines.

Basic Information

Product Name	S-Phenylmercapturic Acid
CAS No.	4775-80-8
Molecular Formula	C11H13NO3S
Molecular Weight	239.29 g/mol
Synonyms	N-Acetyl-S-phenyl-L-cysteine; S-PMA; N-Acetyl-S-phenylcysteine; (R)-2-Acetamido-3-(phenylsulfanyl)propanoic Acid; Benzene Metabolite; Phenylmercapturic Acid; SPMA; N-Acetyl-S-(phenyl)-L-cysteine
EINECS	Contact for details

Quality Control

Our S-Phenylmercapturic Acid is manufactured under strict quality systems to ensure the high purity and consistency required for critical analytical applications. Each batch is thoroughly characterized using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided to support your research and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.