Description

Oleoyl Coenzyme A, [Oleoyl-1-14C]- is a radiolabeled derivative of oleoyl-CoA, a crucial intermediate in lipid metabolism. This compound is specifically designed for use as a high-specific-activity tracer in biochemical research, enabling precise tracking and quantification of fatty acid metabolism pathways. It is an essential tool for researchers and scientists in the fields of lipid biochemistry, metabolic disease research, and enzymology, providing critical insights into fatty acid activation, β-oxidation, and complex lipid synthesis.

Application

• Enzyme Kinetics & Mechanism Studies: Used as a radiolabeled substrate to investigate the kinetics and catalytic mechanisms of acyl-CoA synthetases, thioesterases, and other enzymes involved in fatty acid metabolism.
• Lipid Metabolism Pathway Analysis: Essential for tracing and quantifying the flux through pathways such as mitochondrial β-oxidation, peroxisomal fatty acid oxidation, and glycerolipid biosynthesis.
• Metabolic Disorder Research: Applied in studies of diseases like obesity, diabetes, and non-alcoholic fatty liver disease (NAFLD) to understand dysregulated lipid handling.
• In Vitro & Cell-Based Assays: Serves as a key reagent in cell culture experiments and in vitro assay systems to study lipid uptake, trafficking, and utilization.
• Drug Discovery & Screening: Utilized in high-throughput screening (HTS) platforms to identify and characterize novel therapeutics targeting metabolic enzymes.
• Autoradiography & Imaging: The 14C label allows for precise detection and localization in tissue sections or chromatographic analyses for spatial metabolic studies.

Basic Information

Product Name	Oleoyl Coenzyme A, [Oleoyl-1-14C]-
CAS No.	4767-16-2
Molecular Formula	C39H68N7O17P3S * (14C Labeled)
Molecular Weight	~1060.9 g/mol (unlabeled)
Synonyms	Oleoyl-CoA (14C-labeled); [1-14C]Oleoyl-Coenzyme A; (9Z)-Octadec-9-enoyl-CoA (14C); 9-cis-Octadecenoyl-CoA (14C); Coenzyme A, S-(9Z)-1-14C-octadec-9-enoate; Radiolabeled Oleoyl CoA; Fatty Acyl-CoA Tracer; 14C-Oleoyl-CoA
EINECS	Contact for details

Quality Control

Every batch of Oleoyl Coenzyme A, [Oleoyl-1-14C]- is manufactured and controlled to meet the exacting standards required for life science research. Our quality assurance includes rigorous analytical testing to ensure high radiochemical purity, specific activity, and chemical identity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity by HPLC, specific activity, and solvent composition. We adhere to stringent quality management practices to ensure batch-to-batch consistency and reliability for your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store frozen at -20°C or below. This product is hygroscopic (moisture-sensitive) and strictly light-sensitive. For long-term storage, it is recommended to store under an inert atmosphere. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC/MS)	Conforms to structure
Radiochemical Purity (HPLC)	≥ 95%
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Chemical Purity (HPLC)	≥ 90%
Solvent	Ethanol:Water mixture or as specified
Concentration	Custom concentration available

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.