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Elaidoyl Coenzyme A (C18:1) Free*Acid Ap Prox. 90 CAS NO 4752-14-1


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CAS No.:4752-14-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Elaidoyl Coenzyme A (C18:1) Free*Acid Ap Prox. 90 is a high-purity, long-chain fatty acyl-CoA derivative, specifically the trans-isomer of oleoyl-CoA, serving as a critical biochemical reagent and metabolic intermediate. This compound is essential for researchers studying lipid metabolism, enzyme kinetics, and the biochemical pathways of fatty acid oxidation and elongation. It is primarily utilized in pharmaceutical R&D, academic biochemistry laboratories, and the production of diagnostic kits for metabolic disorders.

Application

  • Biochemical Research: Used as a substrate or standard in enzymatic assays for acyl-CoA synthetases, thioesterases, and fatty acid transport proteins.
  • Metabolic Pathway Studies: Critical for in vitro investigations of mitochondrial β-oxidation and peroxisomal fatty acid metabolism.
  • Pharmaceutical Development: Employed in drug discovery programs targeting metabolic diseases, such as diabetes and non-alcoholic fatty liver disease (NAFLD).
  • Diagnostic Manufacturing: Serves as a key component in the formulation of clinical diagnostic assays for measuring specific acyl-CoA species.
  • Enzyme Characterization: Used to determine the substrate specificity and kinetic parameters of novel enzymes involved in lipid biosynthesis.
  • Cell Signaling Research: Applied in studies exploring the role of lipid-derived molecules in cellular signaling pathways.

Basic Information

Product Name Elaidoyl Coenzyme A (C18:1) Free*Acid Ap Prox. 90
CAS No. 4752-14-1
Molecular Formula C39H68N7O17P3S
Molecular Weight 1000.0 g/mol (approx.)
Synonyms trans-9-Octadecenoyl-CoA; Elaidoyl-CoA; (E)-Octadec-9-enoyl-coenzyme A; Coenzyme A, S-elaidoyl-; Elaidic acid-CoA; C18:1 trans-CoA; Fatty Acyl-CoA (C18:1, trans); S-Elaidoylcoenzyme A
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Quality Control

Our Elaidoyl Coenzyme A is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation by mass spectrometry (MS) and/or NMR. Certificates of Analysis (COA) detailing batch-specific results are available upon request, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and easily oxidized. For long-term stability, store desiccated. Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (HPLC/MS) Conforms
Assay (HPLC) Approx. 90% (Free Acid)
Purity (HPLC) ≥90% (Area %)
Water Content (KF) ≤5.0%
Solubility Soluble in water, methanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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