Description

1,2-Di9-cis-Hexa-Decenoyl-Sn-Glycero-3-Phosphocholine is a synthetic, high-purity phospholipid, specifically a phosphatidylcholine with defined fatty acid chains. This compound is critical for creating advanced lipid-based delivery systems and biomimetic membranes due to its precise molecular structure. It is an essential raw material for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require consistent, well-characterized lipids for formulation development.

Application

• Liposome and Nanoparticle Formulation: A key structural component for creating stable, uniform liposomes used in drug delivery, mRNA vaccines, and diagnostic agents.
• Biomembrane Research: Used to construct model cell membranes (e.g., supported lipid bilayers, vesicles) for studying membrane protein interactions, permeability, and cellular processes.
• Excipient in Advanced Therapeutics: Serves as a functional excipient in lipid nanoparticle (LNP) formulations for encapsulating sensitive active pharmaceutical ingredients (APIs) like nucleic acids (siRNA, mRNA).
• Cell Culture & Cryopreservation: Incorporated into media supplements and cryoprotectant formulations to enhance cell membrane integrity and viability.
• Cosmetic & Dermal Delivery Systems: Used in high-end cosmetic formulations to create nanocarriers for improved skin penetration and stabilization of active ingredients.
• Biophysical & Analytical Standards: Acts as a reference standard in chromatography (HPLC, LC-MS) and spectroscopy for quality control and method development in lipid analysis.

Basic Information

Product Name	1,2-Di9-cis-Hexa-Decenoyl-Sn-Glycero-3-Phosphocholine
CAS No.	4724-96-3
Molecular Formula	C46H86NO8P
Molecular Weight	812.15 g/mol
Synonyms	1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC); 1,2-Di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine; (9Z,9'Z)-1,2-Bis(octadec-9-enoyl)-sn-glycero-3-phosphocholine; DOPC (18:1 (δ9-Cis) PC); Phosphatidylcholine, 1,2-dioleoyl-; Dioleoylphosphatidylcholine; PC(18:1/18:1); L-α-Phosphatidylcholine, dioleoyl
EINECS	225-208-8

Quality Control

Our 1,2-Di9-cis-Hexa-Decenoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality systems suitable for pharmaceutical and research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store unopened vials at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Once opened, use promptly and minimize exposure to air and moisture. Allow the product to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (TLC)	Single spot
Fatty Acid Composition	≥ 95% 18:1 (δ9-Cis)
Solvent Content (Residual)	< 1.0% (by GC)
Water Content (KF)	< 1.0%
Peroxide Value	< 1.0 meq/kg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.