Description

2α,5α-Epoxy-1,2-Dihydroakuammilan-17-Oic Acid Methyl Ester is a specialized indole alkaloid derivative, valued for its complex polycyclic structure which serves as a critical intermediate and reference standard in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity, structurally defined building blocks for pharmaceutical development and natural product chemistry. It is primarily utilized by R&D laboratories, fine chemical producers, and academic institutions focused on medicinal chemistry and alkaloid research.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of novel therapeutic agents, particularly those targeting neurological pathways.
• Reference Standard: Used as a high-purity analytical standard in HPLC, LC-MS, and NMR for the identification and quantification of akuammiline-type alkaloids in complex matrices.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and the synthesis of analogs for biological screening.
• Natural Product Synthesis: Employed in total synthesis projects aimed at constructing complex indole alkaloids found in nature.
• Biochemical Research: Investigated for its potential interactions with various biological receptors and enzymes in pharmacological studies.

Basic Information

Product Name	2α,5α-Epoxy-1,2-Dihydroakuammilan-17-Oic Acid Methyl Ester
CAS No.	4684-32-6
Molecular Formula	C22H26N2O4
Molecular Weight	382.46 g/mol
Synonyms	Methyl 2α,5α-Epoxy-1,2-dihydroakuammilan-17-oate; 17-Carbomethoxyakuammiline; Akuammiline, 17-carbomethoxy-; 2α,5α-Epoxy-1,2-dihydroakuammilan-17-oic acid methyl ester; Methyl 2,5-epoxy-1,2-dihydroakuammilan-17-carboxylate; 17-Methoxycarbonylakuammiline; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2α,5α-Epoxy-1,2-Dihydroakuammilan-17-Oic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for research and development. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Loss on Drying	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.