Description

(4S,4Ar,5R,12As)-4-(Dimethylamino)-3,5,10,11,12A-Pentahydroxy-6-Methyl-1,12-Dioxo-1,4,4A,5,12,12A-Hexahydrotetracene-2-Carboxamide is a complex, high-purity tetracycline derivative with significant pharmaceutical relevance. This compound is valued for its precise stereochemistry and functional groups, which are critical for advanced research and development in medicinal chemistry. It serves as a key intermediate or reference standard for scientists and manufacturers in the pharmaceutical, biotechnology, and fine chemical synthesis sectors.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel tetracycline-class antibiotics and other therapeutic agents.
• Reference Standard: Used for analytical method development, validation, and quality control (QC/QA) in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating antibiotic mechanisms of action, bacterial resistance, and structure-activity relationships (SAR).
• Fine Chemical Synthesis: Acts as a starting material or advanced intermediate for the custom synthesis of complex, chiral molecules.
• Academic Research: Utilized in university and institutional labs for chemical and pharmacological studies.

Basic Information

Product Name	(4S,4Ar,5R,12As)-4-(Dimethylamino)-3,5,10,11,12A-Pentahydroxy-6-Methyl-1,12-Dioxo-1,4,4A,5,12,12A-Hexahydrotetracene-2-Carboxamide
CAS No.	4660-26-8
Molecular Formula	C22H24N2O9
Molecular Weight	460.44 g/mol
Synonyms	4-Dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,11,12a-pentahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide; 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,11,12a-pentahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide; Tetracycline derivative intermediate; 6-Deoxy-5-oxytetracycline precursor; (4S,4aR,5S,12aS)-4-(Dimethylamino)-3,5,10,11,12a-pentahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide
EINECS	Contact for details

Quality Control

Our (4S,4Ar,5R,12As)-4-(Dimethylamino)-3,5,10,11,12A-Pentahydroxy-6-Methyl-1,12-Dioxo-1,4,4A,5,12,12A-Hexahydrotetracene-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets exacting standards for research and synthesis. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.