Description

1-Cyclohexyl-3-(2-Morpholinoethyl)Carbodiimide Metho-p-Toluenesulfonate is a water-soluble carbodiimide reagent widely used as a zero-length coupling agent for peptide synthesis and bioconjugation. This compound is critical for facilitating amide bond formation under mild aqueous conditions, making it indispensable for researchers and manufacturers working with sensitive biomolecules. It is primarily needed by the pharmaceutical, biotechnology, and life sciences industries for applications ranging from drug discovery and development to the production of diagnostic reagents and novel biomaterials.

Application

• Peptide Synthesis: A key coupling reagent for solid-phase and solution-phase peptide synthesis, activating carboxylic acids for amide bond formation.
• Protein Cross-linking & Bioconjugation: Used to conjugate proteins, antibodies, or enzymes to other molecules, surfaces, or carriers for diagnostic assays, targeted drug delivery, and immobilized enzyme systems.
• Nucleic Acid Modification: Facilitates the labeling of oligonucleotides with fluorescent dyes or other reporter groups for probes and sequencing applications.
• Polymer & Material Science: Employed in the synthesis and modification of functional polymers, hydrogels, and biomaterials where controlled covalent linkage is required.
• Carbohydrate Chemistry: Assists in the synthesis of glycoconjugates and complex oligosaccharides by mediating ester and amide bond formation.
• Immunoassay Development: Critical for preparing enzyme-labeled antibodies and antigens used in ELISA and other immunoassay platforms.

Basic Information

Product Name	1-Cyclohexyl-3-(2-Morpholinoethyl)Carbodiimide Metho-p-Toluenesulfonate
CAS No.	4641-47-8
Molecular Formula	C₂₁H₃₁N₃O₄S
Molecular Weight	421.56 g/mol
Synonyms	CMC; CMC Hydrochloride (common misnomer); 1-Cyclohexyl-3-(2-morpholin-4-ylethyl)carbodiimide Methanesulfonate p-Toluenesulfonate; (Cyclohexyl)[2-(4-morpholinyl)ethyl]carbodiimide Metho-p-toluenesulfonate; CMEC; 1-Cyclohexyl-3-(2-morpholinoethyl)carbodiimide Methyl-p-toluenesulfonate; Water-Soluble Carbodiimide; WSC; Morpholinoethyl Cyclohexyl Carbodiimide Metho-p-Toluene Sulfonate
EINECS	Contact for details

Quality Control

Our 1-Cyclohexyl-3-(2-Morpholinoethyl)Carbodiimide Metho-p-Toluenesulfonate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency, meeting the stringent requirements for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep container tightly sealed under an inert atmosphere after opening for optimal long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.