Description

2-Aminopurine Riboside is a modified nucleoside analog of adenosine, where the 2-position hydrogen is substituted with an amino group. This structural modification makes it a valuable fluorescent probe and biochemical tool for studying nucleic acid structure, dynamics, and enzyme interactions. It is primarily utilized by researchers and manufacturers in the life sciences and pharmaceutical development sectors. Its unique photophysical properties allow for real-time monitoring of conformational changes in RNA and DNA without significantly perturbing the native structure.

Application

• Fluorescent Nucleic Acid Probe: Used as a site-specific, environmentally sensitive fluorescent label to study RNA folding, protein-RNA interactions, and DNA hybridization kinetics.
• Enzyme Mechanism Studies: Serves as a substrate or inhibitor for enzymes like adenosine deaminase and various kinases, helping elucidate catalytic mechanisms and specificity.
• Antiviral & Anticancer Research: Investigated as a precursor for the synthesis of nucleoside analogs with potential therapeutic activity against viral infections and certain cancers.
• Biophysical Spectroscopy: Employed in fluorescence anisotropy, FRET (Förster Resonance Energy Transfer), and time-resolved fluorescence experiments to probe macromolecular dynamics.
• Diagnostic Assay Development: Incorporated into molecular beacons and other detection platforms for sensitive, sequence-specific nucleic acid detection.
• Biochemical Standard: Used as a reference standard in analytical chromatography (HPLC, LC-MS) for quality control and method validation in nucleotide analysis.

Basic Information

Product Name	2-Aminopurine Riboside
CAS No.	4546-54-7
Molecular Formula	C10H13N5O4
Molecular Weight	267.24 g/mol
Synonyms	2-Aminopurine-9-β-D-ribofuranoside; 2-Aminopurine Ribonucleoside; 2-APR; 9-β-D-Ribofuranosyl-2-aminopurine; 2-Aminoadenosine; 2-AP; 2-Aminopurine-9-β-D-riboside; NSC 146051
EINECS	Contact for details

Quality Control

Every batch of 2-Aminopurine Riboside is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC), identity confirmation, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.