Description

Acetophenone Tosylhydrazone is a specialized organic compound belonging to the class of tosylhydrazones, which are valuable intermediates in synthetic organic chemistry. This compound is particularly significant for its role as a precursor in the preparation of vinyl compounds and other complex molecules via Shapiro and Bamford-Stevens reactions. It is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and plant growth regulators.
• Organic Synthesis Reagent: Employed in Shapiro and Bamford-Stevens reactions for the generation of vinyl anions and subsequent olefination.
• Material Science Research: Serves as a building block for creating specialized polymers and functional organic materials.
• Academic & Industrial R&D: A critical reagent for methodological development and complex molecule construction in laboratory settings.
• Fine Chemical Production: Utilized in the manufacture of flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	Acetophenone Tosylhydrazone
CAS No.	4545-21-5
Molecular Formula	C₁₅H₁₆N₂O₂S
Molecular Weight	288.36 g/mol
Synonyms	1-(1-Phenylethylidene)-2-(4-methylphenyl)sulfonylhydrazine; Acetophenone p-Toluenesulfonylhydrazone; p-Toluenesulfonylacetophenone hydrazone; Tosylacetophenone hydrazone; Acetophenone tosyl hydrazone; ATZH; TSAP; (1-Phenylethylidene)hydrazine 4-methylbenzenesulfonate
EINECS	Contact for details

Quality Control

Our Acetophenone Tosylhydrazone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.