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1,2-Distearoyl-Sn-Glycero-3-Phosphoglycerol,Sodium Salt CAS NO 4537-78-4


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CAS No.:4537-78-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-Distearoyl-Sn-Glycero-3-Phosphoglycerol, Sodium Salt is a high-purity, synthetic phospholipid derivative, specifically a sodium salt of phosphatidylglycerol (PG) with saturated stearoyl chains. This compound is a critical functional component in the formulation of advanced lipid-based delivery systems and biomimetic membranes. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise control over lipid composition for applications ranging from drug delivery to model membrane studies.

Application

  • Liposome & Nanoparticle Formulation: A key phospholipid component for creating stable, anionic liposomes used in drug and gene delivery systems.
  • Biomimetic Membrane Research: Used to construct model cell membranes (e.g., supported lipid bilayers, vesicles) for studying membrane-protein interactions and biophysical properties.
  • Pulmonary Surfactant Mimetics: Serves as a critical ingredient in synthetic lung surfactant formulations for research and therapeutic development.
  • Diagnostic Reagents: Employed in the development of lipid-based reagents for diagnostic assays and imaging.
  • Cosmetic & Dermal Delivery: Functions as a high-performance emulsifier and penetration enhancer in premium cosmetic and transdermal products.
  • Cell Culture & Cryopreservation: Used as an additive in specialized cell culture media and cryoprotectant formulations.

Basic Information

Product Name 1,2-Distearoyl-Sn-Glycero-3-Phosphoglycerol, Sodium Salt
CAS No. 4537-78-4
Molecular Formula C42H82NaO10P
Molecular Weight 801.06 g/mol
Synonyms DSPG-Na; 1,2-Distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium salt; Sodium 1,2-distearoyl-sn-glycero-3-phosphoglycerol; Phosphatidylglycerol (18:0/18:0) sodium salt; PG(18:0/18:0) sodium salt; DSPG; 1,2-Di-O-stearoyl-sn-glycero-3-phospho-(1'-glycerol) sodium salt; L-α-Phosphatidylglycerol (distearyl, sodium salt)
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Quality Control

Our 1,2-Distearoyl-Sn-Glycero-3-Phosphoglycerol, Sodium Salt is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This material is hygroscopic (moisture-sensitive). For long-term storage, keep under an inert atmosphere (e.g., argon or nitrogen). Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (HPLC/MS) Complies
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Residual Solvents (GC) Meets ICH guidelines
Phase Transition Temperature (DSC) Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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