Description

Anhydrochlortetracycline Hydrochloride is a chemically modified derivative of the broad-spectrum antibiotic chlortetracycline. This compound serves as a critical pharmaceutical intermediate and reference standard in the research and development of novel tetracycline-class antibiotics. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in antibiotic development, analytical method validation, and microbiological studies.

Application

• Pharmaceutical Intermediate: A key starting material or precursor in the synthesis of advanced tetracycline derivatives and novel antibiotic compounds.
• Analytical Reference Standard: Used in high-performance liquid chromatography (HPLC), mass spectrometry, and other analytical techniques for method development, validation, and quality control of related pharmaceutical products.
• Microbiological Research: Employed in laboratory studies to investigate the structure-activity relationships (SAR) of tetracycline antibiotics, their mechanisms of action, and bacterial resistance.
• Chemical Synthesis: Serves as a specialized building block in organic chemistry research for creating modified antibiotic structures with potentially improved properties.
• Veterinary Pharmaceutical Development: Used in R&D for animal health products, given the historical use of tetracyclines in veterinary medicine.

Basic Information

Product Name	Anhydrochlortetracycline Hydrochloride
CAS No.	4497-08-9
Molecular Formula	C22H22ClN2O7 • HCl
Molecular Weight	491.33 g/mol (Free base: 454.87 g/mol)
Synonyms	4-Epianhydrochlortetracycline Hydrochloride; 7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Hydrochloride; ATC HCl; Anhydrochlortetracycline HCl; Demeclocycline Related Compound A (Hydrochloride); 4-Epianhydrochlortetracycline HCl
EINECS	Contact for details

Quality Control

Our Anhydrochlortetracycline Hydrochloride is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting standards for research and pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	Yellow to yellowish-brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.