Description

Pentafluorobenzyl p-Toluenesulfonate is a high-purity, specialized chemical reagent primarily used as a versatile derivatization agent and building block in advanced organic synthesis. Its core value lies in the reactive pentafluorobenzyl group, which is instrumental for introducing fluorinated moieties or acting as a protective/activating group in complex molecular architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel fluorinated compounds and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs) and diagnostic agents.
• Agrochemical Synthesis: Used in creating advanced fluorinated pesticides, herbicides, and plant growth regulators.
• Derivatization Agent: Employed in analytical chemistry, particularly in Gas Chromatography (GC) and Mass Spectrometry (MS), for the analysis of acids, alcohols, and phenols to enhance detection sensitivity.
• Material Science Research: Serves as a precursor for synthesizing fluorinated polymers, liquid crystals, and other specialty materials with unique surface properties.
• Protecting Group Chemistry: The pentafluorobenzyl group can act as a protecting group for carboxylic acids and phenols in multi-step synthetic routes.
• Cross-Coupling Reactions: Useful as an electrophile in palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.

Basic Information

Product Name	Pentafluorobenzyl p-Toluenesulfonate
CAS No.	4455-09-8
Molecular Formula	C14H9F5O3S
Molecular Weight	352.28 g/mol
Synonyms	Pentafluorobenzyl Tosylate; 2,3,4,5,6-Pentafluorobenzyl 4-Methylbenzenesulfonate; 4-Methylbenzenesulfonic Acid Pentafluorobenzyl Ester; PFB-Ts; α,α,α,2,3,4,5,6-Octafluoro-p-tolyl p-Toluenesulfonate; Pentafluorobenzyl p-Tosylate; (Pentafluorobenzyloxy)tosyl; Pentafluorobenzyl Tosylate Ester
EINECS	Contact for details

Quality Control

Our Pentafluorobenzyl p-Toluenesulfonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. Each lot is analyzed with modern analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.