Description

Tabersonine is a monoterpenoid indole alkaloid of significant interest in advanced pharmaceutical research and development. Its complex molecular architecture serves as a key intermediate and a privileged scaffold for synthesizing more complex bioactive compounds. This high-purity material is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly those focused on oncology and neurological drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the semi-synthesis of anticancer agents like vinblastine and vincristine analogs.
• Biochemical Research: Used as a reference standard and tool compound in studies of tubulin polymerization inhibition and mitotic arrest mechanisms.
• Natural Product Synthesis: Serves as a complex building block in the total synthesis of other Vinca and Iboga alkaloids.
• Drug Discovery & Development: Employed in high-throughput screening and structure-activity relationship (SAR) studies to develop novel therapeutics.
• Academic Research: Utilized in university and institutional labs for pharmacological and phytochemical investigations.
• Fine Chemical Production: Incorporated into the manufacture of specialized, high-value chemical entities for advanced applications.

Basic Information

Product Name	Tabersonine
CAS No.	4429-63-4
Molecular Formula	C21H24N2O2
Molecular Weight	336.43 g/mol
Synonyms	Vincaleukoblastine, Tabersonine; 16-Epi-Vellosimine; (19S)-19,20-Didehydro-17-hydroxy-1-methylyohimban-16-carboxylic acid methyl ester; Lochnericine precursor; Catharanthus alkaloid; 3-Epihydroxy-16-epivincadifformine; Contact for additional synonyms.
EINECS	224-618-5

Quality Control

Our Tabersonine is produced and tested under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data including HPLC purity, identity confirmation by spectroscopic methods (IR, NMR, MS), and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.