Description

2-Stearoyl-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid, specifically a saturated phosphatidylcholine, widely recognized for its role as a critical building block in advanced lipid-based formulations. Its consistent molecular structure and defined fatty acid chain length make it an essential material for creating stable, reproducible, and biocompatible delivery systems. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced material science sectors for developing liposomes, lipid nanoparticles (LNPs), and other sophisticated biomimetic membranes.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A key structural phospholipid for constructing stable, uniform vesicles used in drug delivery, mRNA vaccines, and diagnostic imaging agents.
• Biomembrane & Model System Research: Essential for creating defined, saturated phospholipid bilayers to study membrane biophysics, protein-lipid interactions, and cellular processes in vitro.
• Excipient in Advanced Drug Products: Used as a functional excipient in injectable and topical formulations to enhance stability, bioavailability, and biocompatibility of active pharmaceutical ingredients (APIs).
• Cosmetic & Dermal Delivery Systems: Incorporated into high-end cosmetic formulations such as nanosomes and niosomes for targeted, sustained release of active ingredients in skincare products.
• Biomaterial & Coating Development: Serves as a foundational material for developing biocompatible coatings for medical devices, biosensors, and tissue engineering scaffolds.
• Analytical Reference Standard: Used as a certified reference material (CRM) in quality control laboratories for the identification and quantification of phospholipids via HPLC, MS, or other analytical techniques.

Basic Information

Product Name	2-Stearoyl-Sn-Glycero-3-Phosphocholine
CAS No.	4421-58-3
Molecular Formula	C46H92NO8P
Molecular Weight	818.20 g/mol
Synonyms	1-Stearoyl-2-hydroxy-sn-glycero-3-phosphocholine; 18:0 Lyso PC; Lyso-Stearoyl Phosphatidylcholine; 1-Stearoyl-2-lyso-sn-glycero-3-phosphocholine; Lysophosphatidylcholine, Stearoyl; L-α-Lysophosphatidylcholine, Stearoyl; sn-Glycero-3-phosphocholine, 2-Stearoyl-; LPC(18:0/0:0)
EINECS	224-588-6

Quality Control

Our 2-Stearoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for research and GMP-grade applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical parameters such as assay, related substances, and residual solvents. We support compliance with relevant pharmaceutical and regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.