Description

Ajmalicine Hydrochloride is a high-purity, pharmaceutically relevant alkaloid salt derived from natural sources. This compound is a critical intermediate and reference standard in the research and development of cardiovascular and neurological therapeutics. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions engaged in drug discovery and quality control processes.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and purity testing of active pharmaceutical ingredients (APIs) and finished drug products in QC/QA laboratories.
• Biochemical Research: Serves as a key reagent and inhibitor in studies investigating adrenergic and serotonergic receptor mechanisms and related neurological pathways.
• Active Pharmaceutical Ingredient (API) Intermediate: Employed in the synthesis and scale-up of more complex therapeutic agents targeting hypertension and mental health disorders.
• Analytical Method Development: Acts as a calibration standard for developing and validating HPLC, LC-MS, and other chromatographic analytical methods.
• Natural Product Isolation & Standardization: Used as a marker compound for the quality control and standardization of herbal extracts containing Rauwolfia species.

Basic Information

Product Name	Ajmalicine Hydrochloride
CAS No.	4373-34-6
Molecular Formula	C21H24N2O3·HCl
Molecular Weight	388.89 g/mol
Synonyms	δ-Yohimbine Hydrochloride; Raubasine Hydrochloride; 17α-Hydroxyyohimban-16α-carboxylic acid methyl ester hydrochloride; 3-Epi-α-yohimbine hydrochloride; Tetrahydroserpentine hydrochloride
EINECS	Contact for details

Quality Control

Our Ajmalicine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure it meets stringent specifications for pharmaceutical and research use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.