Description

Pth-Valine CAS NO 4333-20-4 is a high-purity, protected amino acid derivative essential for advanced peptide synthesis and pharmaceutical research. This compound serves as a critical building block, enabling the precise construction of complex peptide chains while preventing unwanted side reactions at the valine residue. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers requiring reliable, high-quality intermediates for producing therapeutic peptides and novel bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Nα-protected valine derivative for the sequential assembly of peptides.
• Pharmaceutical Intermediate: In the research and development of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation: For the site-specific modification of proteins and other biomolecules.
• Combinatorial Chemistry: As a building block in libraries for drug discovery and screening.
• Biochemical Research: Used in studies of enzyme substrates, inhibitors, and metabolic pathways.
• Fine Chemical Production: For the custom synthesis of specialized peptides and amino acid analogs.

Basic Information

Item	Detail
Product Name	Pth-Valine
CAS No.	4333-20-4
Molecular Formula	C14H18N2O3S
Molecular Weight	294.37 g/mol
Synonyms	N-Phthaloyl-L-valine; L-Valine, N-phthaloyl-; Phthaloylvaline; PTH-Val; N-(Phenyl-1,2-dicarboximido)valine; 2-[(2-Methylpropanoyl)amino]benzoic acid (related form); Phthalimido valine; N-Phthalimido-L-valine
EINECS	Contact for details

Quality Control

Every batch of Pth-Valine is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications for identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing specific results from tests including HPLC assay, chiral purity, and residual solvent analysis is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.