Description

(S)-(+)-2-Butanol CAS NO 4221-99-2 is the dextrorotatory enantiomer of the secondary alcohol 2-butanol, characterized by its chiral center and high optical purity. This specific stereochemistry makes it a valuable chiral building block and resolving agent in asymmetric synthesis. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates for the development of active ingredients and specialty materials.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: Used as a key starting material or resolving agent for producing enantiomerically pure active pharmaceutical ingredients (APIs).
• Agrochemical Production: Serves as a precursor for chiral pesticides and herbicides where biological activity is stereospecific.
• Fine Chemical and Fragrance Manufacturing: Employed in the synthesis of specialty esters and other compounds where the (S)-configuration imparts specific olfactory or chemical properties.
• Asymmetric Catalysis and Ligand Synthesis: Utilized in the preparation of chiral ligands and catalysts for stereoselective reactions.
• Solvent for Specialty Applications: Acts as a chiral solvent in certain analytical and research contexts where solvent chirality influences reaction outcomes.
• Academic and Industrial Research: A critical reagent for methodological development in organic chemistry and process optimization.

Basic Information

Product Name	(S)-(+)-2-Butanol
CAS No.	4221-99-2
Molecular Formula	C4H10O
Molecular Weight	74.12 g/mol
Synonyms	(S)-(+)-sec-Butyl Alcohol; (S)-2-Butanol; (S)-(+)-Butan-2-ol; (2S)-Butan-2-ol; D-(+)-2-Butanol; (S)-sec-Butanol; (+)-sec-Butyl Alcohol; (S)-Methyl Ethyl Carbinol
EINECS	224-178-9

Quality Control

Our (S)-(+)-2-Butanol is produced under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity assessment by GC or HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, assay, enantiomeric excess (ee), and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat, sparks, and open flame. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for extended stability, though short-term storage at 15-25°C is acceptable.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Specific Rotation [α]20/D	+13.2° to +14.0° (neat)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.