Description

12A-Deoxytetracycline is a tetracycline-class antibiotic intermediate of significant importance in pharmaceutical synthesis. This compound is valued for its role as a key precursor in the development of advanced antibiotic formulations and for research into novel antimicrobial agents. It is primarily utilized by pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in antibiotic production and life science research.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of tetracycline and related antibiotic APIs.
• Antimicrobial Research: Used as a reference standard and starting material in R&D for new antibacterial compounds.
• Veterinary Medicine: Employed in the development of antibiotic treatments for animal health.
• Biochemical Studies: Serves as a tool compound for studying bacterial protein synthesis inhibition mechanisms.
• Fine Chemical Synthesis: Utilized in custom synthesis and the production of specialized chemical derivatives.

Basic Information

Product Name	12A-Deoxytetracycline
CAS No.	4199-36-4
Molecular Formula	C₂₂H₂₄N₂O₈
Molecular Weight	444.44 g/mol
Synonyms	Doxycycline Impurity C; 6-Deoxy-5-hydroxytetracycline; 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide; 12a-Deoxy-5-hydroxytetracycline; 6-Deoxyoxytetracycline; NSC 529064; Doxycycline EP Impurity C
EINECS	Contact for details

Quality Control

Our 12A-Deoxytetracycline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical intermediate use. Certificates of Analysis (COA) are provided and can be tailored to meet specific client or pharmacopeial requirements (e.g., EP, USP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.