Description

(4S)-7-Chloro-4β-(Dimethylamino)-1,4,4Aβ,5,6,11,12,12Aβ-Octahydro-3,6,10,12A-Tetrahydroxy-6α-Methyl-1,11,12-Trioxo-2-Naphthacenecarboxamide is a complex tetracycline-class intermediate with significant synthetic utility. This compound is valued for its role as a key building block in the research and development of novel antibiotic and pharmaceutical agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of advanced therapeutic molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel tetracycline derivatives and other complex antibiotic molecules.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new anti-infective agents.
• Biochemical Research: Serves as a tool compound in microbiological and pharmacological research to study bacterial protein synthesis inhibition.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for constructing complex polycyclic molecular architectures.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control in pharmaceutical manufacturing.

Basic Information

Product Name	(4S)-7-Chloro-4β-(Dimethylamino)-1,4,4Aβ,5,6,11,12,12Aβ-Octahydro-3,6,10,12A-Tetrahydroxy-6α-Methyl-1,11,12-Trioxo-2-Naphthacenecarboxamide
CAS No.	4199-31-9
Molecular Formula	C₂₂H₂₃ClN₂O₈
Molecular Weight	478.88 g/mol
Synonyms	7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide; 7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide; 4S,4aS,5aR,12aS)-7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide; Tetracycline derivative intermediate; 7-Chloro-4-(dimethylamino)tetracycline intermediate
EINECS	Contact for details

Quality Control

Our (4S)-7-Chloro-4β-(Dimethylamino)-1,4,4Aβ,5,6,11,12,12Aβ-Octahydro-3,6,10,12A-Tetrahydroxy-6α-Methyl-1,11,12-Trioxo-2-Naphthacenecarboxamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.