Description

.Alpha.-D-Glucofuranose, 1,2-o-(1-Methylethylidene)-, 5-(4-Methylbenzenesulfonate) is a high-purity, protected carbohydrate derivative, specifically a tosylated glucofuranose intermediate. This compound is of significant value in synthetic organic and medicinal chemistry as a key building block for the controlled synthesis of complex sugars, nucleosides, and other biologically active molecules. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for advanced process development and API synthesis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel nucleoside analogs and antiviral/anticancer drug candidates.
• Glycochemistry Building Block: Used for the selective functionalization and protection of sugar molecules in the synthesis of complex oligosaccharides and glycoconjugates.
• Agrochemical Research: Serves as an intermediate in developing new carbohydrate-based active ingredients for crop protection.
• Process Chemistry: Employed in route scouting and scale-up activities for the production of specialty fine chemicals.
• Biochemical Probe Synthesis: Utilized to create labeled or modified sugar molecules for metabolic pathway studies and diagnostic applications.
• Academic & R&D: A valuable reagent for methodological development in synthetic organic chemistry laboratories.

Basic Information

Product Name	.Alpha.-D-Glucofuranose, 1,2-o-(1-Methylethylidene)-, 5-(4-Methylbenzenesulfonate)
CAS No.	4056-11-5
Molecular Formula	C16H22O8S
Molecular Weight	374.41 g/mol
Synonyms	5-O-Tosyl-1,2-O-isopropylidene-α-D-glucofuranose; 1,2-O-Isopropylidene-α-D-glucofuranose 5-(p-toluenesulfonate); 1,2:5,6-Di-O-isopropylidene-α-D-glucofuranose 3-O-tosylate (related isomer); α-D-Glucofuranose, 1,2-O-(1-methylethylidene)-, 5-(4-methylbenzenesulfonate); Tosyl Isopropylidene Glucose; 5-O-(p-Tolylsulfonyl)-1,2-O-isopropylidene-α-D-glucofuranose; Protected Glucofuranose Tosylate
EINECS	Contact for details

Quality Control

Our .Alpha.-D-Glucofuranose, 1,2-o-(1-Methylethylidene)-, 5-(4-Methylbenzenesulfonate) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if possible to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.