Description

Arecaidine But-2-Ynyl Ester Tosylate is a specialized organic salt derivative of arecaidine, a natural alkaloid. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel bioactive compounds. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuropharmacology and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of muscarinic acetylcholine receptor (mAChR) ligands and other neuroactive compounds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic agents targeting the central nervous system.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Biochemical Research: Employed in vitro studies to investigate cholinergic signaling pathways and receptor pharmacology.
• Process Development: Used in scaling up synthetic routes for potential drug candidates in preclinical and clinical development stages.

Basic Information

Product Name	Arecaidine But-2-Ynyl Ester Tosylate
CAS No.	499-04-7
Molecular Formula	C₁₇H₂₁NO₅S
Molecular Weight	351.42 g/mol
Synonyms	Arecaidine But-2-ynyl Ester p-Toluenesulfonate; Arecaidine But-2-ynyl Ester Tosylate; 1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxylic Acid 4-Pentyn-2-ynyl Ester p-Toluenesulfonate; Arecaidine 4-Pentyn-2-ynyl Ester Tosylate; Arecaidine Propargyl Ester Tosylate (common name); Arecoline Derivative Tosylate Salt; 3-Carboxy-1-methyl-1,2,5,6-tetrahydropyridine But-2-ynyl Ester p-Toluenesulfonate
EINECS	Contact for details

Quality Control

Our Arecaidine But-2-Ynyl Ester Tosylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.