Description

Lindelofidine is a naturally occurring pyrrolizidine alkaloid with a defined stereochemistry, serving as a key intermediate and reference standard in advanced chemical synthesis. Its significance lies in its role as a versatile chiral building block for the development of pharmaceuticals and bioactive compounds. This high-purity material is essential for research and development laboratories, pharmaceutical companies, and fine chemical manufacturers focused on creating novel therapeutic agents and conducting metabolic studies.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe in metabolic pathway studies and pharmacological research.
• Natural Product Synthesis: Serves as a building block for the total synthesis of other pyrrolizidine alkaloids and related natural products.
• Analytical Standard: Employed in HPLC, LC-MS, and NMR for method development, calibration, and quality control in analytical laboratories.
• Asymmetric Catalysis Studies: Utilized as a substrate or ligand in the development and testing of new chiral catalysts.

Basic Information

Product Name	Lindelofidine
CAS No.	488-06-2
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	(1R,2R,7aR)-1,2-Dihydroxyhexahydro-1H-pyrrolizine; (+)-Lindelofidine; Lindelofidin; 1,2-Dihydroxypyrrolizidine; Turneforcidine; Pyrrolizidine alkaloid P-3
EINECS	207-668-5

Quality Control

Our Lindelofidine is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals, and specifications can be tailored to meet specific research or cGMP starting material requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.